Seminar "Design of biointerfaces for directing biological response of proteins, cells and bacteria"

Description

Surface modifications based on biochemical or biological principles are important tools for the

fabrication of biosensor chips, biomedical devices such as implants, and of drug delivery

carriers. Moreover, well-designed model biointerfaces have substantially contributed in the last

decade to a better insight into fundamental aspects of cell-surface and bacteria-surface

interaction.

The seminar will be conducted by Marcus Textor, ETH Zurich, BioInterfaceGroup, Department of Materials, Zurich, Switzerland. He will provide an overview on tools enabling the surface engineer to tailor the interface of biomaterials and biosensors, with special emphasis on self-assembly approaches of eliminating non-specific adsorption (rendering surfaces “non-fouling” through PEG- or oxazoline-based chemistry) and adding to such a silent surface biological functionalities such as peptides, carbohydrates/sugars, proteins/antibodies, growth factors or vesicles.

He will also address the importance of dynamic, in situ techniques to quantitatively monitor the kinetics of adsorption in the context of both the surface modification by self-assembly as well as the determination of specific biointeractions. The third part will cover the functionalization of particles.

www.surface.mat.ethz.ch

Contacts

Department of Information Technologies in the Fuel and Energy Complex

(812) 232-37-74

E-mail: kittek.ifmo@mail.ru